Nodular amyloidosis of the lung presenting as lung malignancy

Introduction. Amyloidosis is a disease associated with the extracellular deposition of insoluble protein material called amyloid. It can be acquired or hereditary, systemic organ-limited. Nodular pulmonary amyloidosis defined as one more tumefactive amyloid deposits in lungs. Outlines cases. This study presents two cases that were hospitalized at Institute for Pulmonary Diseases to clarify origin lesions detected on computed tomography (CT) scans lung parenchyma. In first case, 78-year-old woman, numerous non-calcified nodules described chest CT. The patient died during hospitalization, and autopsy revealed diffusely distributed greyish-yellow nodular upper middle parts right lung, well form partially calcified both Histological analysis samples from macroscopically confirmed amyloidosis. second male, 58 years old, who was operated rectal adenocarcinoma three ago. A CT scan parenchyma shows tumor nodule localized lower lobe lesion lung. corresponds metastasis colorectal cancer, while found. Conclusion. rare condition, because imaging similarities it difficult distinguish malignant Therefore, part routine practice, definitive diagnosis needs by tissue biopsy.